SMi Source Lesson Drug R&D: Toxicology Principles

  • SMi Source lesson Drug R&D: Toxicology Principles has the following microlearning topics

  • 1. What is the Role of Toxicology in Drug Discovery and Development?

    2. How Does Toxicity Work?

    3. How Do Drugs Affect The Body?

    4. What Is the Relationship Between Dose and Response?

    5. How Might Drugs Affect Development?

  • Lesson Drug R&D: Toxicology Principles teaches these concepts

  • Principles of Toxicology, What is the Role of Toxicology in Drug Discovery and Development?, Toxicology in the Pharmaceutical Industry

    Principles of Toxicology, What is the Role of Toxicology in Drug Discovery and Development?, The Role of Toxicology in Drug Discovery and Development

    Principles of Toxicology, What is the Role of Toxicology in Drug Discovery and Development?, Toxicology Studies in Drug Development

  • Lesson Drug R&D: Toxicology Principles addresses these key points

  • Toxicology in the Pharmaceutical Industry

    • Toxicology is the study of substances that have harmful effects on the body
    • Toxicology is the key component in drug development
    • Toxicology is used to evaluate drug candidates with unknown toxicity
    • A toxicologist looks at both the form and the effects of these substances
    • All substances are toxic at one level or another

    Drugs such as antibiotics are human xenobiotics. However, the term is usually used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on plant and animal life.

    The Role of Toxicology in Drug Discovery and Development

    • How a drug might cause harm
    • Explain chemical basis of toxicity
    • Predict drug's effects

    Toxicology Studies in Drug Development

    • Investigative studies
    • Pathology studies
    • Regulatory studies
  • Lesson Drug R&D: Toxicology Principles introduces and defines these terms

  • Xenobiotic: A chemical which is not a natural component of the organism exposed to it

    Toxicant: A xenobiotic with harmful effects on the body

    LD50: Lethal dose to 50% of test population