Overview, Blood Vessels
Cardiovascular Disease, CVD, Prevalence of CVD
Routine treatments, Pharmacotherapy, Invasive Procedures
New therapies, Approaches
Human Circulatory System:
At an average heart rate of seventy beats per minute, the human heart will beat spontaneously and continuously some three billion times by the age of 80. If all of the vessels in the complex network of arteries, arterioles, capillaries, venules and veins in your body were laid end-to-end, they would extend for about 60,000 miles.
Prevalence of CVD
CVD is comprised of:
Since the early 1900s, cardiovascular disease has accounted for more morbidity and mortality in the U.S. than any other major cause. Heart disease is the number one cause of death and disability in the United States and kills more Americans each year than cancer.
A need for new cardiovascular disease therapies:
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Lloyd-Jones D, et al., for the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics 2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:e21-e181.
Department of Health and Human Services, Centers for Disease Control and Prevention Website. Chronic Disease Overview. Leading Causes of Death United States, 2005 Number of deaths.
Iaizzo PA. General Features of the Cardiovascular System. In: Paul A. Iaizzo, ed. Handbook of Cardiac Anatomy, Physiology, and Devices. United States: Humana Press, Inc.; 2005:3-11.