SMi Source Lesson Gastroesophageal Reflux Disease: Food Effect on PK and PD

  • SMi Source lesson Gastroesophageal Reflux Disease: Food Effect on PK and PD has the following microlearning topics

    • 1. Efficacy and Bioavailability

    2. Gastroesophageal Reflux Disease (GERD)

    3. PPI Administration Before a Meal

    4. Absorbtion, Cmax, and AUC

    5. Product Labeling and Data Regarding Effect of Food on AUC and Cmax

    6. Enantiomers

    7. Pharmacokinetics and Pharmacodynamics

    8. Clearance

    9. Drug Elimination

    10. Crossover Design

    11. Bioequivalence

    12. Pharmacokinetic Parameters

    13. Bioavailability, Cmax, and AUC

  • Lesson Gastroesophageal Reflux Disease: Food Effect on PK and PD teaches these concepts

    • The Effect of Food on Pharmacokinetics and Pharmacodynamics in the Treatment of GERD, Efficacy and Bioavailability

  • Lesson Gastroesophageal Reflux Disease: Food Effect on PK and PD addresses these key points

    • Efficacy:

    • The measure of the maximum biological response/effectiveness of a drug

    Bioavailability:

    • The fraction of drug that reaches the systemic circulation or the body’s bloodstream

    Cmax:

    • An indicator of maximal drug exposure

    AUC:

    • The primary measure of net drug exposure

  • Lesson Gastroesophageal Reflux Disease: Food Effect on PK and PD is built from these main references. Log into SMi Source for a complete list and details.

    • PDR Medical Dictionary First Edition. 1995 Williams & Wilkins, Baltimore MD. p204

    PDR Medical Dictionary First Edition. 1995 Williams & Wilkins, Baltimore MD. p547

  • Lesson Gastroesophageal Reflux Disease: Food Effect on PK and PD introduces and defines these terms

    • AUC = Area-Under-the-Curve

    Bioavailability: The physiological availability of a given amount of a drug, as distinct from its chemical potency; proportion of the administered dose which is absorbed into the bloodstream.

    Efficacy: The extent to which a specific intervention, procedure, regimen, or service produces a beneficial result under ideal conditions.