The lesson teaches the following:
Goals of Therapy, End-of Treatment Responders with Relapse (RR)
Goals of Therapy, Sustained Response (Sustained Virologic Response; SVR)
Patients with RR:
The main goal of hepatitis C therapy is to completely eradicate the hepatitis C virus.
End-of-treatment responders with relapse (RR): A patient whose HCV RNA was not detectable at the end of therapy but has reappeared 6 months after therapy.
Eradication: Persistent undetectable HCV RNA in the plasma 6 months after treatment.
Sustained virologic responder: A patient with no detectable HCV RNA 6 months after treatment.
Non-responder: Patients with HCV RNA still detected at the end of therapy.
End-of treatment responders with relapse (RR): A patient whose HCV RNA was not detectable at the end of therapy but has reappeared 6 months after therapy.