SMi Source Lesson Hepatology: Treatment Landscape for Primary Biliary Cirrhosis

  • SMi Source lesson Hepatology: Treatment Landscape for Primary Biliary Cirrhosis has the following microlearning topics

    • 1. Treatment Landscape for Primary Biliary Cirrhosis: Introduction

    2. Treatment Landscape for Primary Biliary Cirrhosis: Learning Objectives

    3. Medical terminology

    4. Ursodeoxycholic Acid (UDCA): Mechanisms of Action

    5. Ursodeoxycholic Acid (UDCA): Efficacy

    6. Ursodeoxycholic Acid (UDCA): Safety and Side effects

    7. Ursodeoxycholic Acid (UDCA): Studies

    8. Other Agents

    9. Liver Transplantation for PBC

    10. Knowledge Check: Goals of PBC Treatment

    11. Knowledge Check: UDCA

    12. Knowledge Check: Global PBC Study Group

    13. Knowledge Check: PBC

  • Lesson Hepatology: Treatment Landscape for Primary Biliary Cirrhosis teaches these concepts

    • Treatment Landscape for Primary Biliary Cirrhosis

    Treatment Landscape for Primary Biliary Cirrhosis: Introduction

  • Lesson Hepatology: Treatment Landscape for Primary Biliary Cirrhosis addresses these key points

    • Welcome

    Treatment Landscape for Primary Biliary Cirrhosis (PBC)

    • Standard of Care: Ursodeoxycholic Acid (UDCA) and its role in the treatment of PBC
    • Key Surrogate Endpoint Studies: PBC Global Study Group and UK-PBC Project
    • Liver transplantation

    Introduction

    Evolution of PBC Clinical Presentation and Diagnosis

    • Earlier presentation and diagnosis
    • Earlier treatment
    • Earlier stage of disease

    Goals of Treatment

    • Improve cholestasis
    • Prevention of liver damage
    • Slow progression of liver failure and transplantation

  • Lesson Hepatology: Treatment Landscape for Primary Biliary Cirrhosis is built from these main references. Log into SMi Source for a complete list and details.

    • Parés A. Old and Novel Therapies for Primary Biliary Cirrhosis. Semin Liver Dis. 2014 Aug;34(3):341-51. doi: 10.1055/s-0034-1383733. Epub 2014 Jul 24.

  • Lesson Hepatology: Treatment Landscape for Primary Biliary Cirrhosis introduces and defines these terms

    • PBC = Primary Biliary Cirrhosis

    UDCA = Ursodeoxycholic Acid 

    ALP = Alkaline Phosphatase