SMi Source Lesson Immunology: Autoimmune Disorders and Hypersensitivity

  • SMi Source lesson Immunology: Autoimmune Disorders and Hypersensitivity has the following microlearning topics

    • 1. Introduction: Autoimmune Disorders and Hypersensitivity - Immunopathologies

    2. Introduction: Autoimmune Disorders and Hypersensitivity - Causes and Statistics

    3. Introduction: Hypersensitivity

    4. Hypersensitivity

    5. Autoimmune Diseases Classified as Hypersensitivity Reactions

    6. Limitations

    7. Knowledge Check: Gell-Coombs Classification

    8. Autoimmune Diseases: Introduction

    9. Autoimmune Diseases: Introduction

    10. Knowledge Check: Autoimmune Diseases

    11. Systemic Lupus Erythematosus: Symptoms and Risk

    12. Systemic Lupus Erythematosus: Multisymptom Disease

    13. Systemic Lupus Erythematosus: Failure of Vital Organs

    14. Rheumatoid Arthritis: Patients

    15. Rheumatoid Arthritis: Cell Migration, Neoangiogenesis, and Early Stages

    16. Rheumatoid Arthritis: TH17

    17. Psoriasis: Psoriatic keratinocytes Pathway

    18. Psoriasis: Upregulated Cytokines

    19. Psoriasis Arthritis: Pain and Swelling in Joints

    20. Psoriasis Arthritis: Psoriatic Spondylitis

    21. Ankylosing Spondylitis: Enthesis and Kyphosis

    22. Ankylosing Spondylitis: Heredity

    23. Multiple Sclerosis: Molecular Mimicry

    24. Multiple Sclerosis: T Cells, B Cells, Axon Damage

    25. Multiple Sclerosis: Demyelination

    26. Knowledge Check: Mechanisms of Select Autoimmune Diseases

  • Lesson Immunology: Autoimmune Disorders and Hypersensitivity teaches these concepts

    • Autoimmune Disorders and Hypersensitivity, Introduction: Autoimmune Disorders and Hypersensitivity

  • Lesson Immunology: Autoimmune Disorders and Hypersensitivity addresses these key points

    • Introduction

    • The immune system sometimes makes a mistake in the process of differentiating self-antigens from foreign antigens
    • Most immunopathologies are due to a dysregulation of multiple components
    • Hypersensitivity reactions are pathologic processes that result from specific interactions between antigens and either antibodies or lymphocytes
    • The clinical consequences of immunopathologies span a wide range, from the temporary discomfort of allergies, to chronic pain, tissue injury, and even death

  • Lesson Immunology: Autoimmune Disorders and Hypersensitivity is built from these main references. Log into SMi Source for a complete list and details.

    • Autoimmune Disorders. MedlinePlus. http://www.nlm.nih.gov. Accessed 07/24/2012 (Pg 1, para 1)

    Autoimmune Disorders Merck Professional. http://www.merckmanuals.com Accessed 07/24/2012 (Pg 1, para 1)

    Bolon B. Cellular and Molecular Mechanisms of Autoimmune Disease. 2012;40:216. (Pages 220-224)

    Cotran et al. 1999; 195, A, 2; In: Cotran, RS.; Kumar, V.; Collins, T., editors. Robbins Pathologic Basis of Disease. 6. W.B. Saunders Co; Philadelphia, PA: 1999.

    Janeway et al., Immunobiology,6th Ed.; Garland Science; 2005. p550 para 2
    Autoimmune Disorders Merck Professional. Available at:
    http://www.merckmanuals.com Accessed 07/24/2012(Pg 1, para 1)

    Primary Immunodeficiency. http://www.nichd.nih.gov. Accessed 07/24/2012

    Simmonds MJ, Gough SCL. Genetic Insights into Disease Mechanisms of Autoimmunity. British Medical Bulletin. 2005;71:93-113. (Pg 94, Figure 1 Legend)

    Understanding the Immune System. How It Works.  http://www.niaid.nih.gov. Accessed 07/24/2012 (Pg 3, para 1)