SMi Source Lesson Lupus: Clinical Presentation

  • SMi Source lesson Lupus: Clinical Presentation has the following microlearning topics

    • 1. Introduction: Clinical Presentation of Lupus

    2. Epidemiology

    3. Epidemiology

    4. Epidemiology

    5. Epidemiology of Systemic Lupus Erythematosus (SLE): Lupus Nephritis (LN)

    6. Patient Scenario: CLE

    7. Patient Scenario Follow Up

    8. Clinical Features/Presentation

    9. Symptoms of SLE

    10. Organ Systems Involved

    11. Course of Disease

    12. Patient Scenario: SLE

    13. Diagnosis of SLE

    14. Diagnosis of SLE

    15. 1997 ACR Diagnostic Criteria

    16. Diagnosis of SLE

    17. Standard Measures of Disease Activity Used in Clinical Trials

    18. Diagnosis of SLE

    19. Diagnosis of SLE

    20. Diagnosis of SLE

    21. Patient Scenario: Results from the Rheumatologist

    22. Complications/Comorbidities of SLE

    23. Lupus Nephritis: 2003 ISN-RPS Classification of Lupus Nephritis (LN)

    24. Lupus Nephritis: End-Stage Renal Failure

    25. Cardiovascular Disease (CVD)

    26. Complications/Comorbidities of SLE

    27. Shrinking Lung Syndrome

    28. Neuropsychiatric and Neurocognitive Dysfunction

    29. Complications/Comorbidities of SLE

    30. Patient Scenario

    31. Overlapping Diseases

    32. Mixed Connective Tissue Disease

  • Lesson Lupus: Clinical Presentation teaches these concepts

    • Clinical Presentation of Lupus, Introduction: Clinical Presentation of Lupus

  • Lesson Lupus: Clinical Presentation addresses these key points

    • SLE is a complex, chronic autoimmune disease

    • Complex clinical presentation and course
    • SLE can affect almost every organ system
    • An evolving disease
    • Manifestations develop over time

    Challenging to diagnose

    • Non-specific clinical features
    • Mimic other diseases
    • Diagnostic delay
    • Distress for patient

    Course of disease

    • Variable and unpredictable
    • Bimodal mortality
    • Death ≤ 5 years of diagnosis
      • Active disease
      • High dose corticosteroids
      • Intense immunosuppression
      • Concomitant infections
    • Late deaths
      • Cardiovascular disease
      • Other chronic complications

    While SLE survival has significantly improved, there is no cure.

  • Lesson Lupus: Clinical Presentation is built from these main references. Log into SMi Source for a complete list and details.

    • Buyon JP. Systemic Lupus Erythematosus. Chapter 15 in: Primer on the Rheumatic Diseases. Eds: Klippel JH, Stone JH, Crofford LG, White PH. 13th Ed. 2008. Springer. (Pages 303 and 305)

    Mcelhone K, Abbott J, and The L-S. A Review of Health Related Quality of Life in Systemic Lupus Erythematosus. Lupus. 2006;15:633. (Pg 1, col 1)