SMi Source Lesson Multiple Sclerosis: History

  • SMi Source lesson Multiple Sclerosis: History has the following microlearning topics

    • 1. Disease Overview: Multiple Sclerosis

    2. Disease Overview: Multiple Sclerosis

    3. Timeline: Multiple Sclerosis

    4. Etiology of Multiple Sclerosis

    5. Infectious Factors

    6. Etiology of Multiple Sclerosis

    7. Epidemiology

    8. Mortality

    9. Multiple Sclerosis: Summary

  • Lesson Multiple Sclerosis: History teaches these concepts

    • History of Multiple Sclerosis, Disease Overview, Clinical Presentation

    History of Multiple Sclerosis, Disease Overview, Multiple Sclerosis: Definition

  • Lesson Multiple Sclerosis: History addresses these key points

    • Clinical Presentation:

    • Vision disturbances
    • Movement problems
    • Spasticity or muscle weakness
    • Unusual sensations
    • Bladder/bowel control
    • Fatigue
    • Impaired sleep
    • Impaired memory
    • Heat intolerance

    Multiple sclerosis, or MS, is recognized as the most common cause of neurological disability in young Caucasian adults. 

    Multiple Sclerosis:

    • A chronic inflammatory neurodegenerative disease of the central nervous system characterized by loss of axons and multifocal lesions
    • Multiple Sclerosis = Multiple Scarring

    MS is characterized by:

    • Demyelination
    • Nerve damage
    • Axonal loss

    Autoimmune Disease:

    • Autoreactive T cells
    • Autoantibodies

  • Lesson Multiple Sclerosis: History is built from these main references. Log into SMi Source for a complete list and details.

    • Campagnolo DI, Vollmer TL. Multiple Sclerosis (Updated September 22, 2010). eMedicine from WebMD. March 22, 2011.

    Lassmann H. Models of Multiple Sclerosis: New Insights into Pathophysiology and Repair. Curr Opin Neuro. 2008.

    The Merck Manuals. Multiple Sclerosis (MS). March 22, 2011.

    Trapp B, Nave K. Multiple Sclerosis: An Immune or Neurodegenerative Disorder? Annu. Rev. Neurosci. 2008. 

    Van den Noort S. Signs and Symptoms of Multiple Sclerosis. In: Olek MJ, ed. Multiple Sclerosis. Etiology, Diagnosis, and New Treatment Strategies. United States: Humana Press, Inc; 2005.

    Van der Walt A, H, Kolbe S, Marriott M, Alexandrou E, Gresle M, Egan G, Kilpatrick T. Neuroprotection in multiple sclerosis: A therapeutic challenge for the next decade. Pharmacology & Therapeutics, 126. 2010.

    Wilkins A, Scolding N. Protecting axons in multiple sclerosis. Multiple Sclerosis 2008.