Opioid Dependence and Addiction
Neurobiology of Addiction and Withdrawal
- Neurobiology of Reward
- Addiction, Tolerance, and Withdrawal
- Criteria for dependence/abuse
- Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS®) System
Epidemiology
- Patient demographics
- Emotional, financial, and social costs
- Causes and risk factors
- Complications
Diagnosis and Primary Prevention
- Diagnostic Components
- Patient history/interview
- Clinical examination
- Laboratory tests
- Primary Prevention
Strategies of Abuse-Deterrent Opioids
- Potential for Abuse
- Strategies of Abuse-Resistance
- Physical/chemical barriers
- Agonist/antagonist combinations
- Aversion
- Delivery system
- Prodrug
- Current Status and Challenges