SMi Source Lesson Pharmacokinetics: For Non-PK Scientists

  • SMi Source lesson Pharmacokinetics: For Non-PK Scientists has the following microlearning topics

    • 1. Introduction

    2. What are the Determinants of PK? ADME

    3. Exploring the Models

    4. Intravenous Bolus

    5. Additional PK Parameters

    6. Constant-Rate Regimens

    7. Oral Dosing

    8. PK in Action

    9. Population PK

    10. PK/PD Modeling

    11. Summary

  • Lesson Pharmacokinetics: For Non-PK Scientists teaches these concepts

    • Pharmacokinetics for Non-PK Scientists, Introduction, Pharmacokinetics (PK)

    Pharmacokinetics for Non-PK Scientists, Introduction, Role of Pharmacokinetics in Drug Discovery & Development

  • Lesson Pharmacokinetics: For Non-PK Scientists addresses these key points

    • Pharmacokinetics (PK):

    • A scientific discipline central to drug discovery and development
    • Describes the fate of drugs in the body over time
    • What the body does to the drug

    A drug undergoes processes such as:

    • Absorption
    • Distribution through the body
    • Chemical changes as a result of metabolism
    • Elimination from the body

    Pharmacodynamics:

    • What the drug does to the body

    Pharmacokinetics:

    • Defines drug concentration in the body
    • Linked to:
      • Response of patient
      • Clinical evaluation of medication
    • Impact on:
      • Dose optimization
      • Formulation design and development
      • Toxicology

  • Lesson Pharmacokinetics: For Non-PK Scientists is built from these main references. Log into SMi Source for a complete list and details.

    • Rowland, M. and Tozer T.N., Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, 3rd ed., Baltimore, MD, 1995.

    The Merck Manual.