SMi Source Lesson Diabetes: Introduction to Pharmacokinetics and Pharmacodynamics

  • SMi Source lesson Diabetes: Introduction to Pharmacokinetics and Pharmacodynamics has the following microlearning topics

  • 1. Learning Objectives

    2. Pharmacokinetics (PK) Terminology and Drug Development

    3. Pharmacodynamics (PD) in Drug Discovery and Development

    4. Pharmacodynamics (PD)

    5. Introduction to Pharmacology, Pharmacodynamics and Pharmacokinetics

    6. Example of a Drug Class That Does Not Act at a Receptor

    7. PK/PD Relationship and Drug Therapies

    8. Knowledge Check: Comparison of Pharmacodynamics, Pharmacokinetics, and PK/PD

    9. Basic Pharmacokinetic (PK) Principles and Detailed Parameters

    10. ADME: Distribution

    11. ADME: Volume of Distribution

    12. Volume of Distribution (Vd)

    13. ADME: Metabolism

    14. ADME: Elimination

    15. Half-Life, Clearance, Rates of Processes

    16. Key PD Parameters from a Glucose Clamp Experiment, Pharmacodynamic Parameters in Diabetes

    17. Knowledge Check: Reading a PK Graph

    18. Knowledge Check: Clearance

    19. Knowledge Check: Changing Dose

    20. Lag Time, Characteristics of Common Routes of Drug Administration

    21. Constant Rate Regimens

    22. Knowledge Check: Drug Absorption and Elimination

    23. Insulin: Pharmacological Profile, Factors Affecting Insulin Absorption

    24. Pharmacokinetics of Commonly-Used Insulins

    25. Pharmacokinetics of Human Insulin and Insulin Analogs

    26. Knowledge Check: PD Parameters in Glucose Clamp Experiment

    27. Glucose Infusion Rates in Glucose Clamp Experiments with Long-Acting Insulins

    28. Knowledge Check: GIR Profiles of Insulin Analogs in Patients with Type 2 Diabetes