The lesson teaches the following:

Use of Statistics in Clinical Trials, Introduction, The Use of Statistics in Clinical Trials and Scientific Hypothesis Testing

The Use of Statistics in Clinical Trials

After completing this module, you should be able to:

- Formulate a null hypothesis from the study objective
- Distinguish between type I and type II errors
- Estimate the effect multiplicity has on the magnitude of type I errors
- Define the intent-to-treat principle
- Explain the role of interim analyses
- Estimate how significance level and other design parameters impact sample size
- Interpret statistical tests
- Distinguish statistical significance from clinical relevance

Scientific Hypothesis Testing

- Key element of clinical trials
- Statistical evaluation of therapeutic intervention