SMi Source Lesson Oncology Treatment: Avastin

  • SMi Source lesson Oncology Treatment: Avastin has the following microlearning topics

  • 1. Humanized Monoclonal Antibody, Avastin Targets

    2. Production of Monoclonal Antibodies in Mammalian Cell Lines

  • Lesson Oncology Treatment: Avastin teaches these concepts

  • Avastin, Humanized Monoclonal Antibody, Avastin Targets

  • Lesson Oncology Treatment: Avastin addresses these key points

  • Avastin

    • Humanized monoclonal antibody 
    • Targets the growth factor VEGF-A
    • Prevents growth factor VEGF-A from binding to VEGF receptors 1 and 2 
      • Inhibits angiogenesis or the formation of new blood vessels
      • Reduces the vascular supply of tumors 
      • Prevents the delivery of oxygen and nutrients to the tumor cells
  • Lesson Oncology Treatment: Avastin is built from these main references. Log into SMi Source for a complete list and details.

  • N. Ferrara, K.J. Hillan, W. Novotny. Bevacizumab (Avastin), a Humanized anti-VEGF Monoclonal Antibody for Cancer Therapy. Biochemical and Biophysical Research Communications. 333:328-335, 2005.